Mr. Southwell has been Executive Vice President and Chief Financial Officer of Sepracor since June 1994. During this time,
Sepracor and its subsidiaries have raised approximately $3.0 billion in three equity, and nine convertible debt financings. More recently, Sepracor repurchased or exchanged approximately $1.3 billion of convertible bonds. In May 2007, Mr. Southwell assumed the additional responsibility of leadership of corporate planning, development, and licensing.

Prior to joining Sepracor, Mr. Southwell was a Vice President in investment banking with Lehman Brothers in New York. His career at Lehman spanned ten years, and included mergers, acquisitions, leveraged buyouts, restructurings and debt and equity financing transactions. While at Lehman, he managed the IPO of Sepracor in September 1991.

Mr. Southwell holds an MBA from the Tuck School at Dartmouth College, and a BA from Rice University in Houston, Texas. Mr. Southwell serves as Chairman of the Board of BioSphere Medical, Chairman of the MBA Advisory Board of the Tuck School at Dartmouth, and is a member of the board of PTC Therapeutics.