LUNESTA^® brand eszopiclone is a non-narcotic non-benzodiazepine indicated for the treatment of insomnia. Introduced in April 2005, LUNESTA allows patients to fall asleep quickly as well as sleep through the night and may be used by people experiencing transient insomnia as well as long-term by people with chronic insomnia.

For additional information about LUNESTA, please visit the LUNESTA product web site at www.lunesta.com.

Insomnia
Approximately ten percent of adults in the U.S. suffer from chronic insomnia, symptoms of which include difficulty falling asleep, awakening frequently during the night and/or waking up too early with an inability to fall back to sleep, resulting in patients feeling unrefreshed.

Important Safety Information: LUNESTA works quickly and should only be taken immediately before bedtime. Patients should have at least eight hours to devote to sleep before becoming active. Patients should not engage in any activity after taking LUNESTA that requires complete alertness, such as driving a car or operating machinery. Patients should use extreme care when engaging in these activities the morning after taking LUNESTA. Patients should not use alcohol while taking any sleep medicine. Most sleep medicines carry some risk of dependency. As with all sleep medicines, somnambulism (sleepwalking), including eating or driving while not fully awake, with amnesia for the event, has been reported. Additionally, rare cases of severe allergic reactions have been reported. Patients who report these events should discontinue treatment and should not be rechallenged with LUNESTA. Patients should not use sleep medicines for extended periods without first talking to their doctor. Patients should see their doctor if they experience unusual changes in thinking or behavior, or if sleep problems do not improve in 7 to 10 days as this may be due to another medical condition. Side effects may include unpleasant taste, headache, drowsiness and dizziness. For more information, please see important product information.